Primary Single Domain Antibodies: VHH, VHH-Fc and VNAR

Single domain antibodies are compact, recombinant antigen-binding reagents. They offer an alternative to conventional antibody formats across molecular biology, cell biology and protein research. Our primary range covers three formats:

• VHH single domain antibodies (nanobodies): single binding domains derived from camelid heavy-chain-only antibodies.
• VHH-Fc fusion antibodies: a VHH binding domain joined to an immunoglobulin Fc region, for selected Fc-based detection and capture workflows.
• VNAR single domain antibodies: a structurally distinct format derived from shark immunoglobulin new antigen receptors (IgNARs).

Choose by target, species reactivity, formulation and validated applications, and check the product datasheet before ordering.

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GMP aligned manufacture of cell culture media, buffers and reagents in the UK. We produce anything from small trial batches up to 2,000 litres backed by ISO 9001 and ISO 13485 accredited quality systems.