Life Science Group Announces Cutting-Edge Collaborative Partnership with Somnus Scientific and Creonate Manufacturing

Life Science Group (LSG) has agreed to a collaborative partnership with Somnus Scientific and Creonate Manufacturing for the next phase of product development.

As part of this, our existing lab-based immunoassay (ELISA) method for measuring propofol will be developed into a rapid point-of-care immunoassay (LFT) test providing all the requirements specified by clinicians.

Dr Tim Craft, Somnus CEO said: “We have been working with LSG’s antibody production team for some time to successfully produce antibodies to propofol and this agreement now provides a clear path from the feasibility work to high-volume manufacturing.”

Both LSG and Creonate complement the work of Somnus and will combine to accelerate us towards our first product.  LSG develops and optimises antibodies in the UK and Creonate was born out of a need for the UK to have secure lateral flow device (LFD) production capabilities during the COVID pandemic and is now operating as the largest independently owned contract manufacturing facility in Europe. 

Dr Craft continued: “We expect to complete production of a prototype LFD in near final manufactured form in just three months. This will result in 100 prototype LFDs being supplied in a test cassette or cartridge of our choice. We will then commence clinical useability testing and remain on target for market launch in 2026.”

Jenny Murray, Managing Director of LSG added, “This partnership represents a significant milestone in our mission to help advance healthcare solutions. By combining our expertise with that of Somnus and Creonate, we are ready to make a meaningful impact in the field of point-of-care testing, ultimately improving patient outcomes and driving innovation in healthcare.

Kevin Woolston, MD of Creonate added, “Considering and ensuring manufacturability at the earliest point of development will add value and de-risk later down the line, aiding a smooth transition through to routine manufactured product, and we are incredibly proud to be collaborating with LSG on this pioneering project for Somnus Scientific”

LSG and Creonate are based close to Somnus’ laboratory in St Neots, this will facilitate easy working arrangements including the testing of human samples on our gold standard HPLC assay, part of the validation programme. In addition, one of our primary clinical test sites, Addenbrookes Hospital, Cambridge is nearby.

Life Science Group Ltd (LSG) is a UK-based manufacturing company specialising in custom biological and in vitro products for global pharmaceutical, biotechnology, contract research organisations, and universities. With four divisions: Life Science Production, Biospecimens, Antibody Production Service, and Diagnostic Kit Services, LSG ensures quality, traceability, and integrity while offering tailored solutions from cell culture products to antibody production and diagnostic kits, thus driving innovation in biotechnology.

Creonate Manufacturing is a privately owned UK SME. We specialise in point of care lateral flow diagnostic manufacture which includes but is not limited to, reagent manufacture, deposition, lamination, assembly, kitting, packing, storage and shipping. Our facility and team are fully agile, and we’re able to support small one-off orders right through to routine scale contracts. We’re ISO13485 certified and our aim is to be a collaborative business that supports its customers with efficient, reliable and cost-effective solutions as a contract manufacturing organisation.

Somnus Scientific’s core technologies are novel sensors for the measurement of blood propofol.  We have published patents to protect our intellectual property and are using the sensors to develop rapid propofol monitors that work at clinically relevant concentrations.  The Company has raised £2 million under SEIS/EIS approved funding rounds and successful grant applications.  Clinician investors account for over 50% of our shareholders and will become champions as our products are launched.  They represent international support for our company, coming from Australia and New Zealand, USA, and Europe.